We are on the forefront developing next generation hazard and risk assessment and predictive toxicology tools. Read More
We use technologies such as gene insertion/deletion with CRISPR Cas9, gene silencing, and next generation sequencing to investigate the impacts of toxicants on genomes and genomic expression. Read More
We investigate biological phenomenon on and across multiple scales – from the transduction of a signal across the phosphorylation and transcriptional networks, to the distribution of a toxicant throughout the body, to the decision-making behavior of individuals within a population. Read More
Epigenetic mechanisms underlying phenotypic plasticity induced by multiple abiotic stressors: harsh environment and insensitive munitionsCapabilitiesThis project will build up a new ERDC capability in environmental epigenetics. It addresses the needs of mechanism-based and more accurate environmental risk assessment (ERA) of military unique substances (MUS) and activities. Environment-induced epigenetic imprinting is an emerging issue in ERA,… Read More
APCRP: Development of ResistanceAlert – a prototype computational biology-based early warning system of herbicide resistance for invasive aquatic plant managementProductMutations occur randomly or in response to selective pressure; however, not all mutations confer herbicide resistance. As an integral part of invasive aquatic plant management, chemical control through use of registered aquatic herbicides and algicides is… Read More
Purpose: Synthetic Biology (SynBio) offers great promise in providing the Army new technologies for solving material, sensing, and human performance oriented challenges. Army use of these technologies requires a full understanding of products’ effects and potential environmental impacts. However, much uncertainty exists as how these biological technologies will impact the environment when used or released… Read More
Improved force protection and maneuverability Predict TIC/TIM threats for mission planning and operational awareness, enable commanders to chose COAs with full knowledge of potential hazards and impacts to troops and maneuverability. -Tools for predicting the impact to force protection of accidental and intention release of TIC/TIMS -Intelligence overlays for threat avoidance and predictions of safe… Read More
We are the Environmental Genomics and Systems Biology (EGSB) Team, part of the ERDC Environmental Laboratory. Our mission is simple: to provide customers and stakeholders with innovative solutions to their complex, biologically oriented problems using a comprehensive approach that is both multiscale and multidisciplinary. Read More